A US NGO has launched the MADE SAFE product safety certification mechanism. The MADE SAFE Seal is the first national certification mark in the US specifically for non-toxic products targeting human health. It currently offers non-toxic certification standards for household cleaning products, personal care products, and baby products. The purpose of this non-toxic product certification mechanism is to promote products free of any chemicals harmful to humans or the environment. Through this mark, consumers can help identify safe products. MADE SAFE has established a database of thousands of known chemicals, addressing their behavioral toxicity, carcinogenicity, developmental toxicity, endocrine disruption, flame retardants, genetic modification, heavy metals, neurotoxicity, high-risk pesticides, reproductive toxicity, harmful solvents, and harmful volatile organic compounds. When applying for product certification, manufacturers must sign a MADE SAFE certification process agreement and agree to provide a list of raw materials, additives, and auxiliary agents used in the product manufacturing process. They must also provide Material Safety Data Sheets (MSDS) for these raw materials and chemicals. The MADE SAFE review team provides companies with information, compares them against a database of hazardous chemicals, and assesses the potential pollution risks of products across the supply chain. Finally, it evaluates the bioaccumulation, environmental sustainability, general toxicity, aquatic toxicity, and ecotoxicity of key chemicals. Only products that pass these rigorous review processes can obtain MADE SAFE certification.